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This is usually a slow-growing (indolent) lymphoma, although some follicular lymphomas can grow quickly.

Follicular lymphomaĪbout 1 out of 5 lymphomas in the United States is a follicular lymphoma. There are several other subtypes of DLBCL, but these are rare. This is a fast-growing lymphoma, but it usually responds well to treatment. It can also block the superior vena cava (the large vein that returns blood to the heart from the arms and head), which can make the arms and face swell. It can grow quite large and can cause trouble breathing because it often presses on the windpipe (trachea) leading into the lungs. It starts in the mediastinum (the area in the middle of the chest behind the breastbone). This type of lymphoma occurs mostly in young women. Overall, about 3 out of 4 people will have no signs of disease after the initial treatment, and many are cured.Ī subtype of DLBCL is primary mediastinal B-cell lymphoma. It can also start in other areas such as the intestines, bones, or even the brain or spinal cord.ĭLBCL tends to be a fast-growing (aggressive) lymphoma, but it often responds well to treatment. It usually starts as a quickly growing mass in a lymph node deep inside the body, such as in the chest or abdomen, or in a lymph node you can feel, such as in the neck or armpit. The average age at the time of diagnosis is mid-60s. The lymphoma cells look fairly large when seen with a microscope.ĭLBCL can affect people of any age, but it occurs mostly in older people. This is the most common type of NHL in the United States, accounting for about 1 out of every 3 lymphomas. The most common types of B-cell lymphomas are listed below. These are types of lymphoma that affect B lymphocytes. B-cell lymphomas make up most (about 85%) of the non-Hodgkin lymphomas (NHL) in the United States.